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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC7A All Species: 19.39
Human Site: S446 Identified Species: 42.67
UniProt: Q9ULT0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULT0 NP_065191.2 858 96185 S446 E C V K L R P S D P T V P L M
Chimpanzee Pan troglodytes XP_515455 862 96398 S426 E C V K L R P S D P T V P L M
Rhesus Macaque Macaca mulatta XP_001113346 857 95745 S446 E C V K L R P S D P T V P L M
Dog Lupus familis XP_531812 812 91373 C412 P L M A A K V C I G S L H W L
Cat Felis silvestris
Mouse Mus musculus Q8BGB2 858 96138 S447 E C M K L Q P S D P T V P L M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506427 843 94241 D429 E C I R L K P D D A T I P L L
Chicken Gallus gallus NP_001026226 809 91043 T442 E C A K L R P T D P T V P L L
Frog Xenopus laevis NP_001090571 843 94707 E429 E C I R L K P E D A T I P L L
Zebra Danio Brachydanio rerio NP_001074072 844 94521 D430 E C I R L K P D D P T I P L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624273 818 92931 S440 K A L Q R E T S N S Q G M Q S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784188 844 94184 D433 G C S N V Q P D N V T V L L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.7 96.7 88.2 N.A. 88.3 N.A. N.A. 50.3 67.7 50.7 50.2 N.A. N.A. 34.2 N.A. 38.5
Protein Similarity: 100 94.5 98.2 91.9 N.A. 94.5 N.A. N.A. 71.9 80.3 71.5 71.6 N.A. N.A. 55 N.A. 58.5
P-Site Identity: 100 100 100 0 N.A. 86.6 N.A. N.A. 53.3 80 53.3 60 N.A. N.A. 6.6 N.A. 33.3
P-Site Similarity: 100 100 100 33.3 N.A. 100 N.A. N.A. 86.6 93.3 86.6 93.3 N.A. N.A. 33.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 10 0 0 0 0 19 0 0 0 0 0 % A
% Cys: 0 82 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 28 73 0 0 0 0 0 0 % D
% Glu: 73 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 28 0 0 0 0 0 10 0 0 28 0 0 0 % I
% Lys: 10 0 0 46 0 37 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 10 0 73 0 0 0 0 0 0 10 10 82 55 % L
% Met: 0 0 19 0 0 0 0 0 0 0 0 0 10 0 37 % M
% Asn: 0 0 0 10 0 0 0 0 19 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 82 0 0 55 0 0 73 0 0 % P
% Gln: 0 0 0 10 0 19 0 0 0 0 10 0 0 10 0 % Q
% Arg: 0 0 0 28 10 37 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 0 46 0 10 10 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 10 10 0 0 82 0 0 0 0 % T
% Val: 0 0 28 0 10 0 10 0 0 10 0 55 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _